International Journal of Hematology

DOI: 10.1007/s12185-009-0262-0 Pages: 348-351

Intravascular large B-cell lymphoma with involvement of the abdominal subcutis: a case report and literature review

1. Peking University Health Science Center, Department of Pathology

2. Peking University China-Japan Friendship Hospital, Department of Hematology

3. Peking University China-Japan Friendship Hospital, Department of Pathology

Correspondence to:
Cuiling Liu



Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of diffuse large B-cell lymphoma (DLBCL). It commonly presents with a variety of symptoms due to occlusion of small vessels by tumor cells in different organ systems. Clinically patients may present with generalized symptoms such as fever and malaise. In western patients, there is a ‘cutaneous variant’ of IVLBCL, which demonstrates cutaneous involvement only. However, Asian patients show hemophagocytosis, which is typical of the ‘Asian variant’. Here we report a case of IVLBCL in a Chinese individual who presented with a huge mass in the subcutis of the abdomen.

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