International Journal of Hematology

DOI: 10.1007/s12185-018-2523-2 Pages: 647-651

Three cases of spontaneous splenic rupture in malignant lymphoma

1. Tokai University School of Medicine, Division of Hematology/Oncology, Department of Internal Medicine

2. Tokai University School of Medicine, Department of Radiology

3. Tokai University School of Medicine, Department of Pathology

Correspondence to:
Jun Amaki
Tel: +81-463-93-1121



Spontaneous splenic rupture is a rare but often life-threatening condition. However, there is no consensus on appropriate management for this condition, due to its rarity. Here, we report three cases of malignant lymphoma with spontaneous splenic rupture. In each case, progression of splenic bleeding was rapid and complicated by malignant lymphoma. Spontaneous splenic rupture complicated by malignant lymphoma may cause exacerbation of anemia and hypovolemic shock. When splenic rupture is indicated by abdominal pain, tachycardia, or hypotension in a patient with splenomegaly, abdominal examination should be performed immediately, and emergency transcatheter arterial embolization and/or splenectomy should be considered.

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